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Phosphonoformic acid trisodium salt hexa
CAS No. 34156-56-4
Phosphonoformic acid trisodium salt hexa ( foscarnet sodium hexahydrate | Sodium phosphonatoformate hexahydrate )
产品货号. M28595 CAS No. 34156-56-4
膦甲酸三钠盐六是一种用于治疗巨细胞病毒视网膜炎的抗病毒化合物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 1G | ￥235 | 有现货 |
|
生物学信息
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产品名称Phosphonoformic acid trisodium salt hexa
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述膦甲酸三钠盐六是一种用于治疗巨细胞病毒视网膜炎的抗病毒化合物。
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产品描述Phosphonoformic acid trisodium salt hexa is an antiviral drug for the treatment of CMV retinitis.
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体外实验Foscarnet sodium (Phosphonoformic acid) inhibit the human cytomegalovirus DNA polymerase (UL54) by mimicking the pyrophosphate leaving group of the nucleotide transfer reaction.Foscarnet sodium (Trisodium phosphonoformate) inhibits Influenza A Victoria (IC50=29 μM), Influenza B HK (IC50=61 μM), and Avian myeloblastosis virus (IC50=5-8 μM), HSV-1, several strains (IC50=0.4-3.5 μM).
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体内实验——
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同义词foscarnet sodium hexahydrate | Sodium phosphonatoformate hexahydrate
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通路Others
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靶点Other Targets
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受体α1-adrenoceptor
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研究领域——
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适应症——
化学信息
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CAS Number34156-56-4
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分子量126.01
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分子式CH3O5P
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(P(O)(O)=O)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Roquebert J, et al. Inhibition of the alpha 1 and alpha 2-adrenoceptor-mediated pressor response in pithed rats by raubasine, tetrahydroalstonine and akuammigine. Eur J Pharmacol. 1984 Oct 30;106(1):203-5.
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